参考资料: [1] https://www./articles/nature26140 [2] Llovet, J. M. et al. Hepatocellular carcinoma. Nat. Rev. Dis. Primers 2,16018–16023 (2016). [3] Schulze, K. et al. Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets. Nat. Genet. 47,505–511 (2015). [4] Kenerson, H. L. et al. Akt and mTORC1 have different roles during liver tumorigenesis in mice. Gastroenterology 144, 1055–1065 (2013). [5] Guri, Y. et al. mTORC2 promotes tumorigenesis via lipid synthesis. Cancer Cell 32, 807–823 (2017). [6] Makowska, Z. et al. Gene expression analysis of biopsy samples reveals critical limitations of transcriptome-based molecular classifcations of hepatocellular carcinoma. J. Pathol. Clin. Res. 2, 80–92 (2016). [7] Vogelstein, B. et al. Cancer genome landscapes. Science 339, 1546–1558(2013). [8] Vijayakrishnan, J. et al. A genome-wide association study identifes risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. Leukemia 31, 573–579 (2017). [9] Lesseur, C. et al. Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. Nat. Genet. 48, 1544–1550 (2016). |
|