【Author】 WANG Wei-wei,ZHANG Hong-miao,ZHANG Ying,LI Jie-ru.Department of Cardiology, the Second Affiliated Hospital of Kunming Medical College,Kunming 060031,China 【机构】 云南昆明医学院第二附属医院干疗心内科;
【摘要】 目的探讨老年高血压患者高尿酸血症与缺血性脑卒中发生的相关性。方法分析100例60岁以上老年原发性高血压患者,根据尿酸水平分为对照组(尿酸≤417μmol/L,51例)和实验组(尿酸≥417μmol/L,49例),比较两组血尿酸水平与缺血性脑卒中之间的关系。结果两组在年龄、体质指数(BMI)、饮酒史、糖尿病史等一般情况方面差异无统计学意义(P>0.05)。入院时的尿酸水平,吸烟史及脑卒中发生率差异有统计学意义(P<0.05)。实验组不同时间段各组间尿酸和脑卒中严重程度评分均有统计学意义(P<0.05)。Logistic回归分析发现,调整脑卒中的其他危险因素后,实验组的脑卒中的发生率是对照组的2.88倍(β=1.059,OR=2.884,P=0.03)。结论尿酸水平增高与老年原发性高血压患者脑卒中发生密切相关。 【Abstract】 Objective To investigate the relationship between blood uric acid and ischemic stroke in the elderly with hypertension.Methods Totally 100 elderly patients with hypertension were divided into study group(blood uric acid≥417μmol/L,n=49) and control group(blood uric acid<417μmol/L,n=51).The relationship between the level of uric acid and ischemic stroke were analyzed in two groups.Results There were not significant differences in age,body mass index (BMI),smoking and drinking,diabetes(P>0.05... 更多
【Key words】 Hypertension; Uricacid; Ischemicstroke; 【中文主题词】高血压*;卒中*;高尿酸血症*;尿酸;病人;因素分析, 统计学;对照组;统计学;人体质量指数;Logistic模型 【英文主题词】Hypertension*;Stroke*;Hyperuricemia*;Uric Acid;Patients;Factor Analysis, Statistical;Control Groups;Statistics;Body Mass Index;Logistic Models 【基金】 云南省教育厅科研基金(2010Y180) |
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