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结论 Germline testing should be considered for all patients with a new diagnosis of pancreatic cancer, regardless of family history - Identification of germline BRCA mutation should prompt consideration of platinum-based therapy for patients with metastatic disease, followed by maintenance with a PARP inhibitor (olaparib) for those exhibiting good disease control Somatic (tumor) testing should be considered for patients as well, with occasional mutations/genetic alterations informing treatment options (eg, immune checkpoint inhibitors) or identifying patients for appropriate clinical trials
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