5种健康生活方式,降低60%阿尔茨海默症风险!
这些健康的生活方式不止能让美国人健康长寿,对于中国人也一样有用。在中国心血管代谢疾病和癌症队列(4C)研究中定义了7条符合中国人情况的ICVHM标准并分析了这些指标与糖尿病、心血管疾病之间的关系。
实际上,有利于心血管代谢健康的指标与有益于大脑健康的指标有不少相通之处,即使是没被CHAP研究和MAP研究纳入评分标准的体重指数、血糖、血压、胆固醇等指标其实也在一定程度上与认知障碍有关[14],而保持健康的认知功能和有效治疗糖尿病之间也是相辅相成的关系[14]。 不抽烟、少喝酒、迈开腿、健康饮食、多动脑子,你保持健康习惯的每一天都是以后成为耳聪目明的朝阳大妈、最强大脑的西城大爷的资本! 往期精彩文章 [2] GBD 2016 Dementia Collaborators. Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019;18(1):88-106. doi:10.1016/S1474-4422(18)30403-4. [3] 2020 Alzheimer's disease facts and figures [published online ahead of print, 2020 Mar 10]. Alzheimers Dement. 2020;10.1002/alz.12068. doi:10.1002/alz.12068. [4] Kivipelto M, Mangialasche F, Ngandu T. Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease. Nat Rev Neurol. 2018;14(11):653-666. doi:10.1038/s41582-018-0070-3. [5] Ghana K, Evans DA, Rajan KB, et al. Healthy lifestyle and the risk of Alzheimer dementia: Findings from 2 longitudinal studies. Neurology published online June 17, 2020. doi:10.1212/WNL.0000000000009816. [6] Bienias JL, Beckett LA, Bennett DA, Wilson RS, Evans DA. Design of the Chicago Health and Aging Project (CHAP). J Alzheimers Dis. 2003;5(5):349-355. doi:10.3233/jad-2003-5501. [7] Bennett DA, Schneider JA, Buchman AS, Mendes de Leon C, Bienias JL, Wilson RS. The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort. Neuroepidemiology. 2005;25(4):163-175. doi:10.1159/000087446 [8] Hannah Joy. Combine 4 or 5 Healthy Lifestyle Traits to Keep Alzheimer's at Bay. June 18, 2020. Health Watch. Available via /news/healthwatch/combine-4-or-5-healthy-lifestyle-traits-keeps-alzheimers-at-bay-195543-1.htm on 2020-06-19. [9] Minn Post. Available via /second-opinion/2020/06/combined-4-5-healthy-behaviors-linked-to-a-60-reduction-in-risk-of-alzheimers-disease/ on 2020-06-19. [10] Corlin L, Short MI, Vasan RS, Xanthakis V. Association of the Duration of Ideal Cardiovascular Health Through Adulthood With Cardiometabolic Outcomes and Mortality in the Framingham Offspring Study [published online ahead of print, 2020 Mar 11]. JAMA Cardiol. 2020;5(5):1-8. doi:10.1001/jamacardio.2020.0109. [11] Li Y, Schoufour J, Wang DD, et al. Healthy lifestyle and life expectancy free of cancer, cardiovascular disease, and type 2 diabetes: prospective cohort study. BMJ. 2020;368:l6669. Published 2020 Jan 8. doi:10.1136/bmj.l6669. [12] Wang T, Lu J, Su Q, et al. Ideal Cardiovascular Health Metrics and Major Cardiovascular Events in Patients With Prediabetes and Diabetes. JAMA Cardiol. 2019;4(9):874-883. doi:10.1001/jamacardio.2019.2499. [13] Li M, Xu Y, Wan Q, et al. Individual and Combined Associations of Modifiable Lifestyle and Metabolic Health Status With New-Onset Diabetes and Major Cardiovascular Events: The China Cardiometabolic Disease and Cancer Cohort (4C) Study [published online ahead of print, 2020 Jun 15]. Diabetes Care. 2020;dc200256. doi:10.2337/dc20-0256. [14] Srikanth V, Sinclair AJ, Hill-Briggs F, Moran C, Biessels GJ. Type 2 diabetes and cognitive dysfunction-towards effective management of both comorbidities. Lancet Diabetes Endocrinol. 2020;8(6):535-545. doi:10.1016/S2213-8587(20)30118-2.
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