要介绍IBD就要先从IBS说起。IBS-identity by state译为序列一致片段,是指在两个及以上个体间存在完全相同的DNA片段即为IBS片段;IBD-identity by descent译为同源相同片段,是在两个及以上个体存在来源于同一祖先的、未发生重组的、完全相同的DNA片段,这样的片段即为IBD片段。所以从定义来看,我们可以说一个IBD片段一定也是IBS片段,但一个IBS片段可以不是IBD片段。下面这张图形象地描绘了何为IBD
Han Z, Hu Y, Tian Q, et al. Genomic signatures and candidate genes of lint yield and fibre quality improvement in Upland cotton in Xinjiang[J]. Plant Biotechnology Journal, 2020.
选择压
Albrechtsen, Anders et al. “Natural selection and the distribution of identity-by-descent in the human genome.” Genetics vol. 186,1 (2010): 295-308. doi:10.1534/genetics.110.113977
驯化历史
Liang Z, Duan S, Sheng J, et al. Whole-genome resequencing of 472 Vitis accessions for grapevine diversity and demographic history analyses[J]. Nature communications, 2019, 10(1): 1-12.
参考资料
Identity by descent https://en./wiki/Identity_by_descent#cite_note-Albrechtsen.2010-21
Identical by descent https:///wiki/Identical_by_descent
Zhou Y, Browning S R, Browning B L. A fast and simple method for detecting identity by descent segments in large-scale data[J]. The American Journal of Human Genetics, 2020.