分享

生活大爆炸之辅酶Q10|一图读懂

 中国生命营养 2021-03-06

「极养视界」科普实验室 原创出品

授权方可转载

图片

作者|Penny MS

校稿|Haoran PHD   编审|Xinyin PHD, RD

设计|Fay

阅读信息 📖

难度:★★   类型:一图读懂

点击查看高清图文

图片

图片

极养视点
  • 辅酶Q10是脂溶性的维生素类似物,辅助各种酶的作用;

  • 辅酶Q10是细胞产生能量的关键物质,具有抗氧化能力;

  • 有一定证据支持,辅酶Q10能够降低体内炎症,在特定人群中能改善心血管(如心衰)的健康;

  • 辅酶Q10能否有效控制三高、预防老年痴呆、治疗偏头痛或预防癌症还需要更多研究去证明;

  • 老年人、慢性病患者和长期服用他汀类药物或华法林钠片的人需要格外关注自身辅酶Q10的水平;

  • 辅酶Q10的食物来源包括沙丁鱼、动物肝脏、牛肉、猪肉、鸡肉、十字花科蔬菜等。

🔗 3大亮点4大准则,“无死角”分析中美差异|美国居民膳食指南 2020-2025

🔗 膳食补充剂NMN:掉落凡间的“长生不老仙丹”?!

🔗 我的食欲,我做主!

🔗 守卫肠道健康,远离癌症魔掌|本周聚焦[No.51期]

《极养日历 2021|湖水历》

现货出售

私享内心澄澈安宁

身之所向 慢食本味

心之所向 静听湖声

⛰️

点击获取上线优惠

值得期待的诚意之作

参考文献

[1] Fan L, Feng Y, Chen G, Qin L, Fu C, Chen L. Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Pharmacological Research. 2017;119:128-136. doi:10.1016/j.phrs.2017.01.032.

[2] Zhai J, Bo Y, Lu Y, Liu C, Zhang L. Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis. PLOS ONE. 2017;12(1):e0170172. doi:10.1371/journal.pone.0170172.

[3] Sale ST, Parvez H, Yeltiwar RK, Vivekanandan G, Pundir AJ, Jain P. A comparative evaluation of topical and intrasulcular application of coenzyme Q10 gel in chronic periodontitis patients: A clinical study. J Indian Soc Periodontol. 2014 Jul;18(4):461-5. doi: 10.4103/0972-124X.138690.

[4] Mortensen S, Rosenfeldt F, Kumar A et al. The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure. JACC: Heart Failure. 2014;2(6):641-649. doi:10.1016/j.jchf.2014.06.008.

[5] DiNicolantonio J, Bhutani J, McCarty M, O'Keefe J. Coenzyme Q10 for the treatment of heart failure: a review of the literature. Open Heart. 2015;2(1):e000326. doi:10.1136/openhrt-2015-000326.

[6] Shao L, Ma A, Figtree G, Zhang P. Combination Therapy With Coenzyme Q10 and Trimetazidine in Patients With Acute Viral Myocarditis. Journal of Cardiovascular Pharmacology. 2016;68(2):150-154. doi:10.1097/fjc.0000000000000396.

[7] Lei L, Liu Y. Efficacy of coenzyme Q10 in patients with cardiac failure: a meta-analysis of clinical trials. BMC Cardiovascular Disorders. 2017;17(1). doi:10.1186/s12872-017-0628-9.

[8] Busanello E, Marques A, Lander N et al. Pravastatin Chronic Treatment Sensitizes Hypercholesterolemic Mice Muscle to Mitochondrial Permeability Transition: Protection by Creatine or Coenzyme Q10. Frontiers in Pharmacology. 2017;8. doi:10.3389/fphar.2017.00185.

[9] Okeahialam B. Reversal of statin-induced memory dysfunction by co-enzyme Q10: a case report. Vascular Health and Risk Management. 2015:579. doi:10.2147/vhrm.s90551.

[10] Suksomboon N, Poolsup N, Juanak N. Effects of coenzyme Q10 supplementation on metabolic profile in diabetes: a systematic review and meta-analysis. Journal of Clinical Pharmacy and Therapeutics. 2015;40(4):413-418. doi:10.1111/jcpt.12280.

[11] Henriksen JE, Andersen CB, Hother-Nielsen O, Vaag A, Mortensen SA, Beck-Nielsen H. Impact of ubiquinone (coenzyme Q10) treatment on glycaemic control, insulin requirement and well-being in patients with Type 1 diabetes mellitus. Diabet Med. 1999;16(4):312-318.

[12] Xu Z, Huo J, Ding X et al. Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition. Scientific Reports. 2017;7(1). doi:10.1038/s41598-017-08899-7.

[13] Sikorska M, Lanthier P, Miller H et al. Nanomicellar formulation of coenzyme Q10 (Ubisol-Q10) effectively blocks ongoing neurodegeneration in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model: potential use as an adjuvant treatment in Parkinson's disease. Neurobiology of Aging. 2014;35(10):2329-2346. doi:10.1016/j.neurobiolaging.2014.03.032.

[14] Muthukumaran K, Leahy S, Harrison K et al. Orally delivered water soluble Coenzyme Q10 (Ubisol-Q10) blocks on-going neurodegeneration in rats exposed to paraquat: potential for therapeutic application in Parkinson’s disease. BMC Neuroscience. 2014;15(1):21. doi:10.1186/1471-2202-15-21.

[15] Parkinson Study Group QE3 Investigators, Beal M, Oakes D et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52. doi:10.1001/jamaneurol.2014.131.

[16] Zhu Z, Sun M, Zhang W, Wang W, Jin Y, Xie C. The efficacy and safety of coenzyme Q10 in Parkinson’s disease: a meta-analysis of randomized controlled trials. Neurological Sciences. 2016;38(2):215-224. doi:10.1007/s10072-016-2757-9.

[17] Negida A, Menshawy A, El Ashal G et al. Coenzyme Q10 for Patients with Parkinson';s Disease: A Systematic Review and Meta-Analysis. CNS & Neurological Disorders - Drug Targets. 2016;15(1):45-53. doi:10.2174/1871527314666150821103306.

[18] Bjørklund G. The Adjuvant Nutritional Intervention in Cancer (ANICA) Trial. Nutrition and Cancer. 2015;67(8):1357-1360. doi:10.1080/01635581.2015.1085582.

[19] Liu H, Cheng S, Huang Y, Huang Y, Lin P. Coenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery. Nutrients. 2017;9(1):29. doi:10.3390/nu9010029.

[20] Tafazoli A. Coenzyme Q10 in breast cancer care. Future Oncology. 2017;13(11):1035-1041. doi:10.2217/fon-2016-0547.

[21] Landbo C, Almdal TP. Interaction between warfarin and coenzyme Q10. Ugeskr Laeger. 1998 May;160(22) 3226-3227. PMID: 9621803.

[22] Tarry-Adkins JL, Fernandez-Twinn DS, Madsen R, et al. Coenzyme Q10 Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth. Endocrinology. 2015;156(10):3528-3537. doi:10.1210/en.2015-1424.

    本站是提供个人知识管理的网络存储空间,所有内容均由用户发布,不代表本站观点。请注意甄别内容中的联系方式、诱导购买等信息,谨防诈骗。如发现有害或侵权内容,请点击一键举报。
    转藏 分享 献花(0

    0条评论

    发表

    请遵守用户 评论公约

    类似文章 更多