Division of diffuse gliomas into adult-type and paediatric-type | 弥漫性胶质瘤分为成人型和儿童型 |
The fifth edition recognizes the clinical and molecular distinctions between diffuse gliomas that occur primarily in adults (termed “adult-type”) and those that occur primarily in children (termed “paediatric-type”). | 第五版认识到主要发生在成人(称为“成人型”)和主要发生在儿童(称为“儿童型”)的弥漫性胶质瘤之间的临床和分子差异。 |
Note the use of the word “primarily” here; paediatric-type tumours may sometimes occur in adults, particularly younger adults, and adult-type tumours may (more rarely) occur in children. | 注意这里使用了“主要”一词;儿童型肿瘤有时可能发生在成年人,尤其是年轻人,而成人型肿瘤可能(更罕见)发生在儿童。 |
Nonetheless, the division of the classification into adult-type and paediatric-type diffuse gliomas is hoped to be a major step forward in clearly separating these clinically and biologically distinct groups of tumours. | 尽管如此,将弥漫性胶质瘤分为成人型和儿童型有望成为明确区分这些临床和生物学上不同的肿瘤组的重要一步。 |
The need to do so has been considered for a long time, but the elucidation of molecular differences has now made this possible. | 长期以来,人们一直在考虑这样做的必要性,但现在对分子差异的阐明使这成为可能 |
It is specifically hoped that this distinction will enable better care of children with brain tumours. | 我们特别希望这种区别能够更好地照顾患有脑瘤的儿童。 |