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”罕见”中的”常见”——EGFR ex20ins治疗进展到哪一步了?【医学】

 zjnbyys 2022-11-17 发布于浙江

参考文献

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3. Oxnard GR, Lo PC, Nishino M, et al. Natural history and molecular characteristics of lung cancers harboring EGFR exon 20 insertions. J Thorac Oncol. 2013;8(2):179-184. doi:10.1097/JTO.0b013e3182779d18

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8. Jorge SE, Kobayashi SS, Costa DB. Epidermal growth factor receptor (EGFR) mutations in lung cancer: preclinical and clinical data. Braz J Med Biol Res. 2014;47(11):929-939. doi:10.1590/1414-431X20144099

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10. Lee JK, Shin JY, Kim S, et al. Primary resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer harboring TKI-sensitive EGFR mutations: an exploratory study. Ann Oncol. 2013;24(8):2080-2087. doi:10.1093/annonc/mdt127

11. Arcila ME, Nafa K, Chaft JE, et al. EGFR exon 20 insertion mutations in lung adenocarcinomas: prevalence, molecular heterogeneity, and clinicopathologic characteristics. Mol Cancer Ther. 2013;12(2):220-229. doi:10.1158/1535-7163.MCT-12-0620

12. Bazhenova L, Minchom A, Viteri S, Bauml JM, Ou SI, Gadgeel SM, Trigo JM, Backenroth D, Li T, Londhe A, Mahadevia P, Girard N. Comparative clinical outcomes for patients with advanced NSCLC harboring EGFR exon 20 insertion mutations and common EGFR mutations. Lung Cancer. 2021 Dec;162:154-161. doi: 10.1016/j.lungcan.2021.10.020. Epub 2021 Nov 6. PMID: 34818606.

13. Oxnard GR, Lo PC, Nishino M, et al. Natural history and molecular characteristics of lung cancers harboring EGFR exon 20 insertions. J Thorac Oncol. 2013 8(2):179-184. doi:10.1097/JTO.0b013e3182779d18

14. Yoon S, Lim SM, Jung HA, et al. Clinical Characteristics, Treatment Patterns and Outcomes of EGFR exon 20 insertion and other EGFR mutations in Korean aNSCLC Patients. 2022 ELCC 50P.

15. Hou J, Li H, Ma S, et al. EGFR exon 20 insertion mutations in advanced non-small-cell lung cancer: current status and perspectives. Biomark Res. 2022 Apr 13;10(1):21. doi: 10.1186/s40364-022-00372-6.

16. Kwon CS, Lin HM, Crossland V, et al. Non-small cell lung cancer with EGFR exon 20 insertion mutation: a systematic literature review and pooled analysis of patient outcomes [published online ahead of print, 2022 May 27]. Curr Med Res pin. 2022;1-34. doi:10.1080/03007995.2022.2083326

17. Kitadai R, Okuma Y. Treatment Strategies for Non-Small Cell Lung Cancer Harboring Common and Uncommon EGFR Mutations: Drug Sensitivity Based on Exon Classification, and Structure-Function Analysis. Cancers (Basel). 2022;14(10):2519. doi: 10.3390/cancers14102519

18. NCCN Clinical Practice Guidelines in Oncology-Non-small cell lung cancer, version 2[J]. J Natl Compr Canc Netw, 2021

19. 中国临床肿瘤学会指南工作委员会.2022 CSCO非小细胞肺癌诊疗指南[J].人民卫生出版社.

20. 杨雪, 赵军. EGFR外显子20插入突变阳性NSCLC治疗的临床研究进展[J]. 中国肺癌杂志, 2022, 25(5):14.

截至2022年9月20日,Mobocertinib(莫博赛替尼)尚未获得中国国家药品监督管理局(NMPA)批准,以上信息仅供医疗卫生专业人士了解学术进展使用,武田公司不推荐说明书外应用。

审核编号: VV-MEDMAT-71717
批准日期: 2022/07
声明: 仅供医疗卫生专业人士为了解资讯使用。该等信息不能以任何方式取代专业的医疗指导,也不应被视为诊疗建议。如该等信息被用于了解资讯以外的目的,本站及作者不承担相关责任

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