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2011-04-212011-07-26
弥散张量成像在脑肿瘤中的应用
李伟龙晚生罗学毛蔡小琴兰勇陈曼琼
[摘要]目的探讨脑肿瘤弥散张量成像(DTI)的特点及其在脑肿瘤中的诊断和鉴别诊断价值。
方法对39例经病理证实的脑肿瘤患者（脑膜瘤10例，胶质瘤17例，转移瘤12例），采用Philips
Achieva1.5T磁共振行常规MRI和DTI，在工作站上重建部分各向异性(FA)图、表观弥散系数(ADC)
图和三维白质纤维束图，选择肿瘤核心实质区和对侧镜像区为兴趣区，测量FA和ADC值，并进行t检
验。结果脑膜瘤、转移瘤和胶质瘤的FA值分别为0.36±0.08、0.28±0.03、0.18±0.06，FA值在脑膜
瘤与转移瘤、脑膜瘤与胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义(P＜0.05)。脑膜瘤、转移瘤
和胶质瘤的ADC值分别为1.72±0.10、1.52±0.22、1.34±0.14，ADC值在脑膜瘤与转移瘤、脑膜瘤与
胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义（P＜0.05）。结论DTI对脑膜瘤、转移瘤和胶质瘤
的鉴别具有很高的临床价值。
磁共振成像，弥散；脑肿瘤
ApplicationofdiffusiontensorimaginginbraintumorsLONGWan-shengLUOXue-maoCAI
Xiao-qinLAN-YongCHENMan-qiongDepartmentofRadiology,JiangmenCentralHospital,Jiangmen
529030,China
10.3760/cma.j.issn.1673-422X.2011.10.025
529030江门市中心医院放射科
[Abstract]ObjectiveTostudythecharacteristicsofdiffusiontensorimaging(DTI)inbraintumor
andit''sdiagnosisanddifferentialdiagnosisvalue.MethodsThirty-ninepatientswithbraintumorsprovenby
pathologically(10meningioma,17glioma,12metastatictumors)wereenrolled,byusingPhilipsAchieva
1.5TMRI,conventionalMRIandDTIwereunderwentonthem,fractionalanisotropy(FA)maps,apparent
diffusioncoefficient(ADC)mapsandthreedimensionalwhitematterfiberbundlemapwerereconstructedin
theworkstation.Thecoresubstanceofthetumorareaandthecontralateralmirrorareawereselectedasthe
regionofinterest,andFAandADCvaluesofthemweremeasured,andttestwasperformed.ResultsTheFA
万方数据
valuesofmeningioma,metastasestumorsandgliomaswere0.36±0.08,0.28±0.03,0.18±0.06,respec
tively,andthedifferencesamongthemweresignificant(P＜0.05).TheADCvaluesofmeningioma,metasta
sestumorsandgliomaswere1.72±0.10,1.52±0.22,1.34±0.14,respectively,andthedifferencesamong
themweresignificant(P＜0.05).ConclusionDTIhashighclinicalvalueinidentificationofmeningiomas,
metastatictumorsandglioma.
Diffusionmagneticresonanceimaging;Brainneoplasms
万方数据
·799·
万方数据
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2011-03-292011-06-30
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