热熔压敏胶在中药透皮吸收制剂中的研究进展

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闫小平,郑蕊,官仕杰,伊博文

(中国中医科学院西苑医院,北京100091)

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June,2009

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[? IóD]

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Applicationofthermoplasticelastomerinhot-meltpressuresensitiveadhesives

fortranstermaldrugdelivery

YANXiaoping,ZHENGRui,GUANShijie,YIBowen

(ChinaAcademyofChineseMedicineSciencesXiyuanHospital,Beijing100091,China)

[Abstract]Developmentofdrugdosageformstoagreatextentdependsonthedevelopmentofdrugauxiliarymaterials.Thede-

velopmentofanewtypeofpolymericdrugauxiliarymaterialswillbringonthedevelopingofanoveldosageformstechnologyandaflood

ofnewdrugdosageforms.Thermoplasticelastomerisanewtypeofdrugpolymericauxiliarymaterials,atpresent,whichhasabroad

applicationinthefieldofhot-meltpressuresensitiveadhesives.ThisreviewmainlydiscussedanewtranstermalChinesedrugdelivery

system,includingmatrixcompositionoftheformula,modifiedthermoplasticelastomerforhot-meltpressuresensitiveadhesivesand

theirdevelopmentprospectsinthetraditionalChinesedrugdeliverysystem.Itsuggestedthatthermoplasticelastomerofhot-meltpres-

suresensitiveadhesiveshasbroaddevelopmentprospectsinthefieldofthetranstermaldrugdeliverysystemfortraditionalChinese

medicine.

[Keywords]thermoplasticelastomer;hot-meltpressuresensitiveadhesives;HMPSA;transtermalChinesedrugdeliverysys-

tem;matrixcomposition;SIS;SBS[3?I?]

#1614#

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2009M6

Vo.l34,Issue12

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