中华糖尿病杂志2019年4月第11卷第4期ChinJDiabetesMellitus，April2019,Vol.11,No.4·247·
的利与弊[J].中国糖尿病杂志,2009,17(12):958,960.DOI:2005,241(6):885-892;discussion892-894.
10.3969/j.issn.1006-6187.2009.12.025.[469]GameF.Managementofosteomyelitisofthefootindiabetes
[458]LipskyBA,HolroydKJ,ZasloffM.Topicalversussystemicmellitus[J].NatRevEndocrinol,2010,6(1):43-47.DOI:
10.1038/nrendo.2009.243.
antimicrobialtherapyfortreatingmildlyinfecteddiabeticfoot
ulcers:arandomized,controlled,double-blinded,multicenter[470]GameFL,JeffcoateWJ.Primarilynon-surgicalmanagementof
trialofpexiganancream[J].ClinInfectDis,2008,47(12):osteomyelitisofthefootindiabetes[J].Diabetologia,2008,51
1537-1545.DOI:10.1086/593185.(6):962-967.DOI:10.1007/s00125-008-0976-1.
[459]LipskyBA,HoeyC.Topicalantimicrobialtherapyfortreating[471]LipskyBA.Treatingdiabeticfootosteomyelitisprimarilywith
surgeryorantibiotics:haveweansweredthequestion?[J].
chronicwounds[J].ClinInfectDis,2009,49(10):1541-1549.
DiabetesCare,2014,37(3):593-595.DOI:10.2337/dc13-2510.
DOI:10.1086/644732.
[472]Aragón-SánchezJ,LipskyBA.Modernmanagementof
[460]LipskyBA,KussM,EdmondsM,etal.Topicalapplicationof
agentamicin-collagenspongecombinedwithsystemicdiabeticfootosteomyelitis.Thewhen,howandwhyof
antibiotictherapyforthetreatmentofdiabeticfootinfectionsconservativeapproaches[J].ExpertRevAntiInfectTher,2018,
16(1):35-50.DOI:10.1080/14787210.2018.1417037.
ofmoderateseverity:arandomized,controlled,multicenter
[473]Lázaro-MartínezJL,Aragón-SánchezJ,García-MoralesE.
clinicaltrial[J].JAmPodiatrMedAssoc,2012,102(3):
Antibioticsversusconservativesurgeryfortreatingdiabetic
223-232.
footosteomyelitis:arandomizedcomparativetrial[J].Diabetes
[461]U?kayI,KressmannB,MalacarneS,etal.Arandomized,
Care,2014,37(3):789-795.DOI:10.2337/dc13-1526.
controlledstudytoinvestigatetheefficacyandsafetyofa
[474]ZeunP,GoodayC,NunneyI,etal.Predictorsofoutcomesin
topicalgentamicin-collagenspongeincombinationwith
diabeticfootosteomyelitistreatedinitiallywithconservative
systemicantibiotictherapyindiabeticpatientswitha
(nonsurgical)medicalmanagement:aretrospectivestudy[J].
moderateorseverefootulcerinfection[J].BMCInfectDis,
IntJLowExtremWounds,2016,15(1):19-25.DOI:10.1177/
2018,18(1):361.DOI:10.1186/s12879-018-3253-z.
1534734615596892.
[462]U?kayI,KressmannB,DiTS,etal.Arandomizedcontrolled
[475]ZenelajB,BouvetC,LipskyBA,etal.Dodiabeticfoot
trialofthesafetyandefficacyofatopicalgentamicin-collagen
infectionswithmethicillin-resistantStaphylococcusaureus
spongeindiabeticpatientswithamildfootulcerinfection[J].
differfromthosewithotherpathogens?[J].IntJLowExtrem
SAGEOpenMed,2018,6:2050312118773950.DOI:10.1177/
Wounds,2014,13(4):263-272.DOI:10.1177/
2050312118773950.
1534734614550311.
[463]LaveryLA,PetersEJ,ArmstrongDG,etal.Riskfactorsfor
[476]EdmondsME,FosterAVM.Stage4:theinfectedfoot.
developingosteomyelitisinpatientswithdiabeticfootwounds
Managingthediabeticfoot[M].3rdedition.London:Wiley
[J].DiabetesResClinPract,2009,83(3):347-352.DOI:
Backewell,2014:147-194.
10.1016/j.diabres.2008.11.030.
[477]ToneA,NguyenS,DevemyF,etal.Six-weekversus
[464]Aragón-SánchezFJ,Cabrera-GalvánJJ,Quintana-MarreroY,
twelve-weekantibiotictherapyfornonsurgicallytreated
etal.Outcomesofsurgicaltreatmentofdiabeticfoot
diabeticfootosteomyelitis:amulticenteropen-labelcontrolled
osteomyelitis:aseriesof185patientswithhistopathological
randomizedstudy[J].DiabetesCare,2015,38(2):302-307.
confirmationofboneinvolvement[J].Diabetologia,2008,51
DOI:10.2337/dc14-1514.
(11):1962-1970.DOI:10.1007/s00125-008-1131-8.
[478]Aragón-SánchezJ,Lázaro-MartínezJL,Hernández-HerreroC,
[465]KhodaeeM,LombardoD,MontgomeryLC,etal.Clinical
etal.Doesosteomyelitisinthefeetofpatientswithdiabetes
inquiry:what′sthebesttestforunderlyingosteomyelitisin
reallyrecuraftersurgicaltreatment?naturalhistoryofa
patientswithdiabeticfootulcers?[J].JFamPract,2015,64(5):
surgicalseries[J].DiabetMed,2012,29(6):813-818.DOI:
309-310,321.
10.1111/j.1464-5491.2011.03528.x.
[466]RajbhandariSM,SuttonM,DaviesC,etal.′Sausagetoe′:a
[479]MutluogluM,LipskyBA.Non-surgicaltreatmentofdiabetic
reliablesignofunderlyingosteomyelitis[J].DiabetMed,2000,
footosteomyelitis[J].LancetDiabetesEndocrinol,2017,5(8):
17(1):74-77.
668.DOI:10.1016/S2213-8587(16)30141-3.
[467]MoralesLR,GonzálezFML,MartinezHD,etal.Validating
[480]Aragón-SánchezFJ.Chapter11:Osteomyelitis:surgical
theprobe-to-bonetestandothertestsfordiagnosingchronic
managemet.HinchliffeRJ,SchaperNC,ThompsonMM,etal.
osteomyelitisinthediabeticfoot[J].DiabetesCare,2010,33
Thediabeticfoot[M].London,UnitedKingdom:JPMedicalLtd,
(10):2140-2145.DOI:10.2337/dc09-2309.
2014:79-91.
[468]HenkePK,BlackburnSA,WainessRW,etal.Osteomyelitis
（收稿日期：2018-12-18）
ofthefootandtoeinadultsisasurgicaldisease:conservative
managementworsenslowerextremitysalvage[J].AnnSurg,（本文编辑：杨颖） |
|
