n．．．ee．。－s－r．Os－－．．．．r．．t．o．it。e．．－c－．－。P－m－iＲl、－Ｒ．．pdn．ofyito．uf．－fij－．－s．．．＜．t、t。、u、．e。Ｒis．e－ximsmldnwrhn－nM．m．cuＲoc．．．vf－tebＲ．trt．．。．Ｒ．．。．－．．Ｒ．hshＲw。．tＲ－－Ｒs－t．s．．．Ｒ．Ｒn．－．Ｒc．．．－－fＲonoi
332Vol33No2
20152CHINESEACHIVESOFTADITIONALCHINESEMEDICINEFeb2015
DOI1013193/jissn1673-7717201502053
pEK1/2
321000
1/2
pEK1/2
30SDNAC10
OVA3pEK1/2
pEK1/2001
EK1/2
pEK1/2
2855A1673-7717201502-0419-03
ECAaIaaaE
PEK1/2aAa
XULidanWANGKaixuanJIXiumeiWANGDayanJIANGXueyan
JinhuaCentralHospitalofZhejiangUniversityHangzhou321000ZhejiangChina
AbaThepurposesofthisstudyweretoobservetheinfluenceofcurcuminoninflammatorycellsinbron-
choalveolarlavagefluidandtheexpressionofpEK1/2inlungtissueinchronicasthmaticratsandalsotoexplorethe
mechanismofinhibitionairwayinflammationandimprovementairwayremodelinginasthmaticrats30maleSD
ratswererandomlydividedonaverageintothreegroupsnormalcontrolgroupNgroupasthmamodelgroupA
curcumingroupgroupCTheasthmaticmodelswereestablishedbyovalbuminOVAThesymptomsofasthmatic
attackandairwayinflammationaswellastheexpressionofpEK1/2proteinafterimmuno-histochemicalstainingwere
observedThesymptomsofasthmaticattackwerethemostobviousintheasthmaticmodelgroupbutmildinthe
20140903
20133045
1985
92J201336547
8
110J201118
1J
109798
2008264775776
9
260
J2011915117
J201327499100
118
335
1036J
J201328141
2012215439
4
11
J2012281145
J20104514344
48
419
12
5
J2013z24849
J20142214215
13
6
J201327111017
J201415456
1018
7 |
|
