NeoplasiaVol.19,No.11,2017EAC-DerivedExtracellularVesicleMicroRNAsKeetal.949
[24]LiL,PiontekK,IshidaM,FaustherM,DranoffJA,FuR,MezeyE,GouldSJ,[37]MunagalaR,AqilF,andGuptaRC(2016).ExosomalmiRNAsasbiomarkersof
FordjourFK,MeltzerSJ,etal(2017).ExtracellularvesiclescarrymicroRNA-195recurrentlungcancer.TumourBiol37(8),10703–10714.https://doi.org/
tointrahepaticcholangiocarcinomaandimprovesurvivalinaratmodel.10.1007/s13277-016-4939-8.
Hepatology65(2),501–514.https://doi.org/10.1002/hep.28735.[38]LiQ,ZouC,ZouC,HanZ,XiaoH,WeiH,WangW,ZhangL,ZhangX,TangQ,
[25]AnT,QinS,XuY,TangY,HuangY,SituB,InalJM,andZhengL(2015).etal(2013).MicroRNA-25functionsasapotentialtumorsuppressorincoloncancer
ExosomesserveastumourmarkersforpersonalizeddiagnosticsowingtotheirbytargetingSmad7.CancerLett335(1),168–174.https://doi.org/
importantroleincancermetastasis.JExtracellVesicles4,27522.10.1016/j.canlet.2013.02.029.
[26]deVrijJ,MaasSL,KwappenbergKM,SchnoorR,KleijnA,DekkerL,Luider[39]ZoniE,vanderHorstG,vandeMerbelAF,ChenL,RaneJK,PelgerRC,
TM,deWitteLD,LitjensM,vanStrienME,etal(2015).Glioblastoma-derivedCollinsAT,VisakorpiT,Snaar-JagalskaBE,MaitlandNJ,etal(2015).miR-25
extracellularvesiclesmodifythephenotypeofmonocyticcells.IntJCancerModulatesInvasivenessandDisseminationofHumanProstateCancerCellsvia
137(7),1630–1642.https://doi.org/10.1002/ijc.29521.Regulationofalphav-andalpha6-IntegrinExpression.CancerRes75(11),
[27]PeinadoH,AleckovicM,LavotshkinS,MateiI,Costa-SilvaB,Moreno-BuenoG,2326–2336.https://doi.org/10.1158/0008-5472.CAN-14-2155.
Hergueta-RedondoM,WilliamsC,Garcia-SantosG,GhajarC,etal(2012).[40]ZhuC,RenC,HanJ,DingY,DuJ,DaiN,DaiJ,MaH,HuZ,ShenH,etal
Melanomaexosomeseducatebonemarrowprogenitorcellstowardapro-metastatic(2014).Afive-microRNApanelinplasmawasidentifiedaspotential
phenotypethroughMET.NatMed18(6),883–891.https://doi.org/biomarkerforearlydetectionofgastriccancer.BrJCancer110(9),
10.1038/nm.2753.2291–2299.https://doi.org/10.1038/bjc.2014.119.
[28]KinoshitaT,YipKW,SpenceT,andLiuFF(2017).MicroRNAsinextracellular[41]ZhangR,WangW,LiF,ZhangH,andLiuJ(2014).MicroRNA-106b~25
vesicles:potentialcancerbiomarkers.JHumanGenet62(1),67–74.https://doi.org/expressionsintumortissuesandplasmaofpatientswithgastriccancers.Med
10.1038/jhg.2016.87.Oncol31(10),243.https://doi.org/10.1007/s12032-014-0243-x.
[29]BigagliE,LuceriC,GuastiD,andCinciL(2016).Exosomessecretedfrom[42]LiJ,YenC,LiawD,PodsypaninaK,BoseS,WangSI,PucJ,MiliaresisC,
humancoloncancercellsinfluencetheadhesionofneighboringmetastaticcells:RodgersL,McCombieR,etal(1997).PTEN,aputativeproteintyrosine
RoleofmicroRNA-210.CancerBiolTherapy,1–8.https://doi.org/10.1080/phosphatasegenemutatedinhumanbrain,breast,andprostatecancer.Science
15384047.2016.1219815.275(5308),1943–1947.
[30]BojSF,HwangCI,BakerLA,ChioII,EngleDD,CorboV,JagerM,[43]ZhangL,ZhangS,YaoJ,LoweryFJ,ZhangQ,HuangWC,LiP,LiM,Wang
Ponz-SarviseM,TiriacH,SpectorMS,etal(2015).OrganoidmodelsofX,ZhangC,etal(2015).Microenvironment-inducedPTENlossbyexosomal
humanandmouseductalpancreaticcancer.Cell160(1-2),324–338.microRNAprimesbrainmetastasisoutgrowth.Nature527(7576),100–104.
https://doi.org/10.1016/j.cell.2014.12.021.https://doi.org/10.1038/nature15376.
[31]FengX,JiangJ,ShiS,XieH,ZhouL,andZhengS(2016).Knockdownof[44]YuP,FanS,HuangL,YangL,andDuY(2015).MIR210asapotential
miR-25increasesthesensitivityoflivercancerstemcellstoTRAIL-inducedmoleculartargettoblockinvasionandmetastasisofgastriccancer.Med
apoptosisviaPTEN/PI3K/Akt/Badsignalingpathway.IntJOncol49(6),Hypotheses84(3),209–212.https://doi.org/10.1016/j.mehy.2014.12.024.
2600–2610.https://doi.org/10.3892/ijo.2016.3751.[45]ChenJ,WangW,ZhangY,ChenY,andHuT(2014).Predictingdistant
[32]DelettreC,YusteVJ,MoubarakRS,BrasM,Lesbordes-BrionJC,PetresS,metastasisandchemoresistanceusingplasmamiRNAs.MedOncol31(1),799.
BellalouJ,andSusinSA(2006).AIFsh,anovelapoptosis-inducingfactor(AIF)https://doi.org/10.1007/s12032-013-0799-x.
pro-apoptoticisoformwithpotentialpathologicalrelevanceinhumancancer.[46]DingL,ZhaoL,ChenW,LiuT,LiZ,andLiX(2015).miR-210,amodulator
JBiolChem281(10),6413–6427.https://doi.org/10.1074/jbc.M509884200.ofhypoxia-inducedepithelial-mesenchymaltransitioninovariancancercell.IntJ
[33]ChowdhuryR,WebberJP,GurneyM,MasonMD,TabiZ,andClaytonA(2015).ClinExpMed8(2),2299–2307.
Cancerexosomestriggermesenchymalstemcelldifferentiationintopro-angiogenic[47]XieQ,LinT,ZhangY,ZhengJ,andBonannoJA(2005).Molecularcloningand
andpro-invasivemyofibroblasts.Oncotarget6(2),715–731.https://doi.org/characterizationofahumanAIF-likegenewithabilitytoinduceapoptosis.JBiol
10.18632/oncotarget.2711.Chem280(20),19673–19681.https://doi.org/10.1074/jbc.M409517200.
[34]LeMT,HamarP,GuoC,BasarE,Perdigao-HenriquesR,BalajL,andLiebermanJ[48]YangW,SunT,CaoJ,LiuF,TianY,andZhuW(2012).Downregulationof
(2014).miR-200-containingextracellularvesiclespromotebreastcancercellmetastasis.miR-210expressioninhibitsproliferation,inducesapoptosisandenhances
JClinInvest124(12),5109–5128.https://doi.org/10.1172/JCI75695.radiosensitivityinhypoxichumanhepatomacellsinvitro.ExpCellRes318(8),
[35]Villarroya-BeltriC,BaixauliF,Gutierrez-VazquezC,Sanchez-MadridF,and944–954.https://doi.org/10.1016/j.yexcr.2012.02.010.
MittelbrunnM(2014).Sortingitout:regulationofexosomeloading.Semin[49]EvanGIandVousdenKH(2001).Proliferation,cellcycleandapoptosisin
CancerBiol28,3–13.https://doi.org/10.1016/j.semcancer.2014.04.009.cancer.Nature411(6835),342–348.https://doi.org/10.1038/35077213.
[36]AclandP,DixonM,PetersG,andDicksonC(1990).Subcellularfateofthe[50]StrotmanLNandLinderMW(2016).ExtracellularVesiclesMoveTowardUsein
int-2oncoproteinisdeterminedbychoiceofinitiationcodon.NatureClinicalLaboratories.ClinLabMed36(3),587–602.https://doi.org/10.1016/
343(6259),662–665.https://doi.org/10.1038/343662a0.j.cll.2016.05.004. |
|
