?????? M.Germain,etal.JournalofControlledRelease326(2020)164–171 [21]M.Valenza,etal.,Cholesterol-loadednanoparticlesamelioratesynapticandcog-s41598-018-23140-9. nitivefunctioninHuntington’sdiseasemice,EMBOMolMed7(2015)1547–1564,[33]H.He,L.Liu,E.E.Morin,M.Liu,A.Schwendeman,Surveyofclinicaltranslationof https://doi.org/10.15252/emmm.201505413.CancerNanomedicines—lessonslearnedfromsuccessesandfailures,Acc.Chem. [22]S.Tiwari,V.Atluri,A.Kaushik,A.Yndart,M.Nair,Alzheimer’sdisease:patho-Res.52(2019)2445–2461,https://doi.org/10.1021/acs.accounts.9b00228. genesis,diagnostics,andtherapeutics,Int.J.Nanomedicine14(2019)5541–5554,[34]C.H.Wong,K.W.Siah,A.W.Lo,Estimationofclinicaltrialsuccessratesandrelated https://doi.org/10.2147/IJN.S200490.parameters,Biostatistics20(2018)273–286,https://doi.org/10.1093/ [23]A.Vilella,etal.,ReducedplaquesizeandinammationintheAPP23mousemodelbiostatistics/kxx069. forAlzheimer’sdiseaseafterchronicapplicationofpolymericnanoparticlesforCNS[35]C.L.Ventola,ProgressinNanomedicine:approvedandinvestigationalNanodrugs,P targetedzincdelivery,J.TraceElem.Med.Biol.49(2018)210–221,https://doi.T42(2017)742–755. org/10.1016/j.jtemb.2017.12.006.[36]J.J.Richardson,F.Caruso,Nanomedicinetoward2040,NanoLett.20(2020) [24]S.M.Metcalfe,S.Bickerton,T.NeurodegenerativeDiseaseFahmy,Aperspectiveon1481–1482,https://doi.org/10.1021/acs.nanolett.0c00620. cell-basedtherapyintheneweraofcell-freeNano-therapy,Curr.Pharm.Des.23[37]TAB,h,www.healthtech-tab.eu. (2017)776–783,https://doi.org/10.2174/1381612822666161206141744.[38]EU-NCL,www.euncl.eu. [25]M.Salvalaio,etal.,Targetedpolymericnanoparticlesforbraindeliveryofhigh[39]K.M.Tyner,etal.,Productqualityfornanomaterials:currentU.S.experienceand molecularweightmoleculesinLysosomalstoragedisorders,PLoSOne11(2016),perspective,WIREsNanomedicineandNanobiotechnology7(2015)640–654, https://doi.org/10.1371/journal.pone.0156452e0156452-e0156452.https://doi.org/10.1002/wnan.1338. [26]J.T.Duskey,etal.,InInternationalReviewofNeurobiologyVol.137(EdsHariS.[40]FDA,DrugProducts,IncludingBiologicalProducts,thatContainNanomaterials- Sharma&ArunaSharma)1–28,AcademicPress,2017.GuidanceforIndustry,https://www.fda.gov/regulatory-information/search-fda- [27]L.Rigon,etal.,TargetingbraindiseaseinMPSII:preclinicalevaluationofIDS-guidance-documents/drug-products-including-biological-products-contain- loadedPLGAnanoparticles,Int.J.Mol.Sci.20(2014),https://doi.org/10.3390/nanomaterials-guidance-industry,(2017). ijms20082014(2019).[41]U.Food,D.Administration,GlobalSummitonRegulatoryScience(GSRS16).Global [28]S.Mizrahy,A.Gutkin,P.Decuzzi,D.Peer,TargetingcentralnervoussystemSummitonRegulatoryScience1(GSRS16)NanotechnologyStandardsandApplications. pathologieswithnanomedicines,J.DrugTarget.27(2019)542–554,https://doi.Bethesda,MD,USA,7–9,(2016). org/10.1080/1061186X.2018.1533556.[42]H.Box,etal.,theREFINEwhitepaper:Anticipationofregulatoryneedsforna- [29]C.Paviolo,P.R.Stoddart,Goldnanoparticlesformodulatingneuronalbehavior,notechnology-enabledhealthproductsEUcommission,(2019). Nanomaterials(Basel)7(2017)92,https://doi.org/10.3390/nano7040092.[43]S.Bremer-Homann,B.Halamoda-Kenzaoui,S.E.Borgos,Identicationofreg- [30]A.Munawar,etal.,Nanosensorsfordiagnosiswithoptical,electricandmechanicalulatoryneedsfornanomedicines,J.InterdisciplinaryNanomed.3(2018)4–15, transducers,RSCAdv.9(2019)6793–6803,https://doi.org/10.1039/https://doi.org/10.1002/jin2.34. C8RA10144B.[44]S.Gioria,F.Caputo,D.Mehn,Nano-enabledmedicinalproducts:timeforanin- [31]N.P.Suh,PrinciplesofDesign,OxfordUniversityPress(NY),1990.ternationaladvancedcommunity?Nanomedicine14(2019)1787–1790,https:// [32]M.Germain,etal.,Primingthebodytoreceivethetherapeuticagenttoredenedoi.org/10.2217/nnm-2019-0173. treatmentbenet/riskprole,Sci.Rep.8(2018)4797,,https://doi.org/10.1038/ 171 |
|