Nature Reviews Microbiology [IF:26.819] Microbiome: Microbiota-based nutrition plans DOI: 10.1038/nrmicro.2015.10 Abstract & Authors 展开 Abstract:
Blood glucose levels after a meal (clinically termed postprandial glycaemic response, or PPGR) are determined by the dietary intake of an individual in combination with additional factors, including the gut microbiota. Importantly, elevated PPGRs are linked to the development of type 2 diabetes mellitus and metabolic syndrome. The links between diet, the gut microbiota and PPGRs are still being elucidated, but a new study has shown that PPGRs to standardized meals are highly variable between individuals and are dependent on multiple factors, including the gut microbiota. Furthermore, monitoring individual responses to different foods and integrating this information with health parameters and microbiome composition in a machine-learning algorithm enabled the elaboration of individualized nutrition plans that improved PPGRs and resulted in consistent alterations in the composition of the gut microbiota. First Authors:
Cláudio Nunes-Alves Correspondence:
Cláudio Nunes-Alves All Authors:
Cláudio Nunes-Alves 2015-12-07
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