由Orito等于2016年提出,旨在探索比点征更细微的对比剂外渗现象。临床发现其不仅可有效预测血肿扩大,且与预后不良显著相关。每例ICH患者均完成2次CTA扫描,分别为CTA期和延迟期(CTA期后5min),设定直径为10mm的感兴趣区(region of interest,ROI),并计算其CT值,延迟期ROI内CT值较CTA期增加>10%的现象定义为渗漏征。该研究发现渗漏征对预测血肿扩大的敏感性及特异性分别为93.3%及88.9%,均高于点征。
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