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因为要使用STAR-fusion软件，其GitHub主页里面提到了配置好的数据库文件，我就想直接下载，如下： ├── [ 26G] GRCh37_gencode_v19_CTAT_lib_Nov012017.plug-n-play.tar.gz
├── [ 20G] GRCh38_gencode_v26_CTAT_lib_Nov012017.plug-n-play.tar.gz
├── [ 21G] Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz
看起来大小差不多，我以为下载完毕，结构解压的时候发现 tar xxvf Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz
Mouse_M15_CTAT_lib_Nov012017/
Mouse_M15_CTAT_lib_Nov012017/ctat_genome_lib_build_dir/
Mouse_M15_CTAT_lib_Nov012017/ctat_genome_lib_build_dir/ref_genome.fa
Mouse_M15_CTAT_lib_Nov012017/ctat_genome_lib_build_dir/pfam_domains.dbm
gzip: stdin: unexpected end of file
tar: Unexpected EOF in archive
tar: Unexpected EOF in archive
tar: Error is not recoverable: exiting now
这个时候才想到去下载日志里面看看，原来是下载失败了。 22023800K .......... .......... .......... .......... .......... 88% 17.2K 5h5m
22023850K .......... .......... .. 88% 126K=9m26s
2018-01-07 23:41:09 (157 KB/s) - Connection closed at byte 22552444928. Retrying.
--2018-01-07 23:41:19-- (try:12) https://data./Trinity/CTAT_RESOURCE_LIB/Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz
Connecting to data.|69.173.92.29|:443... connected.
HTTP request sent, awaiting response... 404 Not Found
2018-01-07 23:41:38 ERROR 404: Not Found.
所以我检查了md5确认了一下，然后断点续下。 wget -c https://data./Trinity/CTAT_RESOURCE_LIB/Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz
--2018-01-09 10:58:23-- https://data./Trinity/CTAT_RESOURCE_LIB/Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz
Resolving data.... 69.173.92.29
Connecting to data.|69.173.92.29|:443... connected.
HTTP request sent, awaiting response... 206 Partial Content
Length: 25502123410 (24G), 2949678482 (2.7G) remaining [application/x-gzip]
Saving to: “Mouse_M15_CTAT_lib_Nov012017.plug-n-play.tar.gz”
88% [+++++++++++++++++++++++++++虽然解决问题了，但是因为当初没有进行md5校验，导致后来的流程报错，浪费了几天时间。
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