活力计算*细胞活力:细胞增殖活力或细胞毒性活力 活力计算:细胞活力×(%)=[A(加药)-A(空白)]/[A(0加药)-A(空白)] ×100 A(加药):具有细胞、CCK-8溶液和药物溶液的孔的吸光度 A(空白):具有培养基和CCK-8溶液而没有细胞的孔的吸光度 A(0加药):具有细胞、CCK-8溶液而没有药物溶液的孔的吸光度 已发表文献数据文献引用Wei, W.J., et al., Obatoclax and LY3009120 Efficiently Overcome Vemurafenib Resistance in Differentiated Thyroid Cancer. Theranostics, 2017. 7(4): p. 987-1001. Shen, C.T., et al., Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo. J Mol Endocrinol, 2017. 58(1): p. 15-23. Jiang, J.Z., et al., Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells. Toxicol In Vitro, 2017. 38: p. 59-66. Liu, X., et al., Rapid hemostatic and mild polyurethane-urea foam wound dressing for promoting wound healing. Mater Sci Eng C Mater Biol Appl, 2017. 71: p. 289-297. Du Z, et al., MicroRNA31-NDRG3 regulation axes are essential for hepatocellular carcinoma survival and drug resistance. Cancer Biomark, 2017. Cao, C., et al., Osteopontin regulates the proliferation of rat aortic smooth muscle cells in response to gingipains treatment. Mol Cell Probes, 2017. Li, X., et al., Placental growth factor silencing ameliorates liver fibrosis and angiogenesis and inhibits activation of hepatic stellate cells in a murine model of chronic liver disease. J Cell Mol Med, 2017. Liu, S., et al., Macrophage infiltration of electrospun polyester fibers. Biomater Sci, 2017. Shi, G., et al., Sox9 facilitates proliferation, differentiation and lipogenesis in primary cultured human sebocytes. J Dermatol Sci, 2017. 85(1): p. 44-50. Liu, Y., et al., uPAR promotes tumor-like biologic behaviors of fibroblast-like synoviocytes through PI3K/Akt signaling pathway in patients with rheumatoid arthritis. Cell Mol Immunol, 2017. Zhang, S., J. Yin and J. Zhong, Chaetocin reactivates the lytic replication of Epstein-Barr virus from latency via reactive oxygen species. Sci China Life Sci, 2017. 60(1): p. 66-71. Wei, W.J., et al., Propranolol sensitizes thyroid cancer cells to cytotoxic effect of vemurafenib. Oncol Rep, 2016. 36(3): p. 1576-84. Zhou, Y., et al., Synergistic anti-liver fibrosis actions of total astragalus saponins and glycyrrhizic acid via TGF-beta1/Smads signaling pathway modulation. J Ethnopharmacol, 2016. 190: p. 83-90. Yang, Q.L., et al., Sweroside ameliorates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice by regulating bile acids and suppressing pro-inflammatory responses. Acta Pharmacol Sin, 2016. 37(9): p. 1218-28. Yang, F., et al., Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXR-miR-22-CCNA2 signaling pathway. Oncotarget, 2016. 7(46): p. 75165-75175. Li, S., et al., DNA Cleavage and Condensation Activities of Mono- and Binuclear Hybrid Complexes and Regulation by Graphene Oxide. Molecules, 2016. 21(7). Liu, T., et al., Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects. Stem Cells Int, 2016. 2016: p. 1416047. Yang, Y., et al., Human CIK Cells Loaded with Au Nanorods as a Theranostic Platform for Targeted Photoacoustic Imaging and Enhanced Immunotherapy and Photothermal Therapy. Nanoscale Res Lett, 2016. 11(1): p. 285. Yang, Y., et al., Human CIK Cells Loaded with Au Nanorods as a Theranostic Platform for Targeted Photoacoustic Imaging and Enhanced Immunotherapy and Photothermal Therapy. Nanoscale Res Lett, 2016. 11(1): p. 285. Li, W., et al., MicroRNA-495 regulates starvation-induced autophagy by targeting ATG3. FEBS Lett, 2016. 590(6): p. 726-38. Wang, H., et al., Notch4 Signaling Pathway of Endothelial Progenitor Cells in a Kawasaki Disease Model Induced by Lactobacillus casei Cell Wall Extract. J Vasc Res, 2016. 53(5-6): p. 340-348. CCK法与其他细胞增殖/毒性检测方法的优势比较
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