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·新冠患者体重减轻是个很常见的症状，研究表明，新冠病毒感染会加剧脂肪从白色脂肪变成褐色脂肪，褐色脂肪可以让糖类和脂肪酸直接分解，不产生ATP，这被称为非颤抖性产热。研究人员让小鼠感染新冠后发现，感染新冠的小鼠在一周内体重下降了20%。因此感染新冠有助于脂肪组织萎缩，体重也会相应减轻。 ·最新的XBB毒株，是一种重组病毒。是两种不同病毒的基因组被重组生成，不仅传播能力更强，还这意味着新冠变异的数量和特征比之前广泛。很可能结合两种变异毒株的优势，逃避免疫，并拥有更强的致病性。因此即使阳过，也不能掉以轻心。 [1] Washburn R L, Hibler T, Kaur G, et al. Sertoli cell immune regulation: A double-edged sword[J]. Frontiers in Immunology, 2022, 13.[2] Nassau D E, Best J C, Kresch E, et al. Impact of the SARS‐CoV‐2 virus on male reproductive health[J]. BJU international, 2022, 129(2): 143-150.[3] Collins A B, Zhao L, Zhu Z, et al. Impact of COVID-19 on male fertility[J]. Urology, 2022.[4] Amin M. COVID-19 and the liver: overview[J]. European Journal of Gastroenterology & Hepatology, 2021.[5] Ashraf U M, Abokor A A, Edwards J M, et al. SARS-CoV-2, ACE2 expression, and systemic organ invasion[J]. Physiological Genomics, 2021.[6] van Eijk L E, Binkhorst M, Bourgonje A R, et al. COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options[J]. The Journal of pathology, 2021, 254(4): 307-331.[7] Hingorani K S, Bhadola S, Cervantes-Arslanian A M. COVID-19 and the Brain[J]. Trends in Cardiovascular Medicine, 2022.[8] Wang M K, Yu X L, Zhou L Y, et al. COVID-19 and liver dysfunction: What nutritionists need to know[J]. World Journal of Gastroenterology, 2022, 28(15): 1526.[9] Li P, Liu Y, Cheng Z, et al. COVID-19-associated liver injury: clinical characteristics, pathophysiological mechanisms and treatment management[J]. Biomedicine & Pharmacotherapy, 2022: 113568.[10] Zhang C, Shi L, Wang F S. Liver injury in COVID-19: management and challenges[J]. The lancet Gastroenterology & hepatology, 2020, 5(5): 428-430.[11] Okor I, Bob-Manuel T, Price J, et al. COVID-19 Myocarditis: An Emerging Clinical Conundrum[J]. Current Problems in Cardiology, 2022: 101268.[12] Ammirati E, Lupi L, Palazzini M, et al. Prevalence, Characteristics, and Outcomes of COVID-19–Associated Acute Myocarditis[J]. Circulation, 2022, 145(15): 1123-1139.[13] Mohammadi A, Balan I, Yadav S, et al. Post-COVID-19 Pulmonary Fibrosis[J]. Cureus, 2022, 14(3).[14] Krygier A, Szmajda-Krygier D, Świechowski R, et al. Molecular Pathogenesis of Fibrosis, Thrombosis and Surfactant Dysfunction in the Lungs of Severe COVID-19 Patients[J]. Biomolecules, 2022, 12(12): 1845.[15] Shafran N, Shafran I, Ben-Zvi H, et al. Secondary bacterial infection in COVID-19 patients is a stronger predictor for death compared to influenza patients[J]. Scientific reports, 2021, 11(1): 1-8.[16] Jing, X., Wu, J., Dong, C. et al. COVID-19 instigates adipose browning and atrophy through VEGF in small mammals. Nat Metab (2022).
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