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Knowledge is power. Get our free daily newsletter. 知识就是力量；每天一篇专业解读，提供可靠医学信息。 
关键词：骨科；文献速览；选题；选刊 做科研、尤其是选题，需要读很多文献；最高效的阅读方式是，先读领域内最受关注的论文。本期我们通过大数据分析，找到了在过去一个月里发表的论文中，骨科（检索词：Orthop*[Affiliation]）领域最受关注的SCI论文，希望对同仁们快速了解本学科最新进展有帮助。如果您想获得全文，请扫码文末的科研助手二维码；请提供对应的文章编号。
1，GDF5与婴儿髋关节发育不良影响因素的关联分析
Association Analysis of GDF5 and Contributing Factors in Developmental Dysplasia of the Hip in Infants. Ortop Traumatol Rehabil. 2021 Oct 31;23(5):335-339. doi: 10.5604/01.3001.0015.4348.
获取全文请找科研助手，标注“20211125-1”。2，腰痛中的人工智能和计算机视觉：系统评价Artificial Intelligence and Computer Vision in Low Back Pain: A Systematic Review. Int J Environ Res Public Health. 2021 Oct 17;18(20):10909. doi: 10.3390/ijerph182010909. 
获取全文请找科研助手，标注“20211125-2”。3，封闭式负压引流与常规引流在跟骨闭合性骨折术后引流中的比较：随机对照试验Comparison of vacuum sealing drainage and conventional drainage for postoperative drainage in closed calcaneal fracture: A randomized controlled trial. Injury. 2021 Oct 21:S0020-1383(21)00890-1. doi: 10.1016/j.injury.2021.10.018.
获取全文请找科研助手，标注“20211125-3”。
4，3D 生物打印载有 BMSC 的仿生多相支架可有效修复骨关节炎大鼠模型中的骨软骨缺损
3D-bioprinted BMSC-laden biomimetic multiphasic scaffolds for efficient repair of osteochondral defects in an osteoarthritic rat model. Biomaterials. 2021 Oct 27;279:121216. doi: 10.1016/j.biomaterials.2021.121216.
获取全文请找科研助手，标注“20211125-4”。5，富血小板血浆注射与安慰剂对踝关节骨关节炎患者踝关节症状和功能的影响：一项随机临床试验Effect of Platelet-Rich Plasma Injections vs Placebo on Ankle Symptoms and Function in Patients With Ankle Osteoarthritis: A Randomized Clinical Trial. JAMA. 2021 Oct 26;326(16):1595-1605. doi: 10.1001/jama.2021.16602. 
获取全文请找科研助手，标注“20211125-5”。6，软组织和内脏肉瘤：ESMO-EURACAN-GENTURIS 诊断、治疗和随访临床实践指南Soft tissue and visceral sarcomas: ESMO-EURACAN-GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆. Ann Oncol. 2021 Nov;32(11):1348-1365. doi: 10.1016/j.annonc.2021.07.006. 
获取全文请找科研助手，标注“20211125-6”。
7，用于部分半月板缺失的生物合成支架：从动物模型到临床实践的系统评价
Biosynthetic scaffolds for partial meniscal loss: A systematic review from animal models to clinical practice. Bioact Mater. 2021 Apr 7;6(11):3782-3800. doi: 10.1016/j.bioactmat.2021.03.033.
获取全文请找科研助手，标注“20211125-7”。8，三维打印个性化多孔植入物：一种用于大骨缺损治疗的新“植入物-骨”界面融合概念Three-dimensional-printed individualized porous implants: A new 'implant-bone' interface fusion concept for large bone defect treatment. Bioact Mater. 2021 Apr 6;6(11):3659-3670. doi: 10.1016/j.bioactmat.2021.03.030.
获取全文请找科研助手，标注“20211125-8”。
9，Z 型细胞外 DNA 是细菌生物膜基质的结构成分Z-form extracellular DNA is a structural component of the bacterial biofilm matrix. Cell. 2021 Nov 11;184(23):5740-5758.e17. doi: 10.1016/j.cell.2021.10.010.
获取全文请找科研助手，标注“20211125-9”。论文是知识的载体，也是成果的体现形式；投稿时选刊非常重要，可让你事半功倍。 在以'orthop*'[Affiliation] AND 2021/8/20:2021/11/20[Date - Publication]为检索词的情况下，过去的3个月里，骨科领域共发表了12,170篇Medline收录的论文，我们对其中的10,998篇进行大数据分析。 全球范围内以梅奥诊所、华西医院和特殊外科医院发表的论文数量最多。 特意查了Hospital for Special Surgery，其骨科在美国排名第一。 
发表骨科论文最多的期刊，依次为：Cureus（非SCI收录）, BMC Musculoskelet Disord（IF 2.054）, J Orthop Surg Res（IF 2）, Arch Orthop Trauma Surg（IF 2.965）, Sci Rep（IF 4.4）等。 特别注意：IF = -1，意味着未被SCI收录。
(最近3个月，发表骨科论文最多的期刊) 这些期刊的分期、发表周期等。
这些研究主要涉及关节置换术、骨关节病等。
D，选题思路借鉴 每一期我们都会分享一位学者发表的论文列表，以期待对大家选题提供借鉴。针对骨科的研究，我们上传选取的是英国牛津大学的Prieto-Alhambra, Daniel。Prieto-Alhambra在过去3个月，发表了5篇论文，侧重于临床数据库建设和预测模型研究，这是最常见的临床科研类型。本次这次选取的是德国的Migliorini, Filippo。
Dr. Migliorini在过去3个月，发表了17篇论文，几乎都是系统综述或者危险因素研究。以从Dr. Migliorini的论文题目中，既学习到如何论文选题；更重要的是，系统综述是对一个研究领域的系统回顾，可以作为临床立题的基础，从而找到临床基金的选题。(2021) Fragility Fractures: Risk Factors and Management in the Elderly Medicina (Kaunas) (2021) Analysis of the pulmonary function in patients undergoing vertebral body tethering for adolescent idiopathic scoliosis Eur Spine J (2021) Autologous Bone Grafting in Trauma and Orthopaedic Surgery: An Evidence-Based Narrative Review J Clin Med (2021) Reliability of the MOCART score: a systematic review J Orthop Traumatol (2021) Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature Eur J Med Res (2021) Slowed-Down Rehabilitation Following Percutaneous Repair of Achilles Tendon Rupture Foot Ankle Int (2021) Allograft Versus Autograft Osteochondral Transplant for Chondral Defects of the Talus: Systematic Review and Meta-analysis Am J Sports Med (2021) Membrane scaffolds for matrix-induced autologous chondrocyte implantation in the knee: a systematic review Br Med Bull (2021) Surgical Management of Focal Chondral Defects of the Talus: A Bayesian Network Meta-analysis Am J Sports Med (2021) Surgical management of focal chondral defects of the knee: a Bayesian network meta-analysis J Orthop Surg Res (2021) Effect of drugs on bone mineral density in postmenopausal osteoporosis: a Bayesian network meta-analysis J Orthop Surg Res (2021) Platelet-rich plasma versus steroids injections for greater trochanter pain syndrome: a systematic review and meta-analysis Br Med Bull (2021) Placebo effect in pharmacological management of fibromyalgia: a meta-analysis Br Med Bull (2021) Correction to: Single‑ versus double‑bundle patellar graft insertion for isolated MPFL reconstruction in patients with patellofemoral instability: a systematic review of the literature Arch Orthop Trauma Surg (2021) Correction to: Patellar fixation graft via suture anchors versus tunnel techniques during isolated MPFL reconstruction for recurrent patellofemoral instability: a systematic review of the literature Arch Orthop Trauma Surg (2021) Correlation between age, coronal and sagittal parameters and spine flexibility in patients with adolescent idiopathic scoliosis Spine Deform (2021) Pharmacological management of secondary spinal cord injury Expert Opin Pharmacother
对Migliorini, Filippo进行检索时发现，Dr. Migliorini已经发表了190篇论文，大都是普通杂志。所以Dr. Migliorini的选题对于医生的选题很有帮助。
期待您能够受到一些启发，找到更好的临床科研方向；研究顺利发表，解决更多临床问题。
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