看来FSH可以成为治疗AD的新靶点呢,毕竟老年男性中也有FSH上升的现象,而且实验也发现无论小鼠雌雄,FSH抗体都能有效改善AD病理。
除了对神经元,其实FSH之前已经被发现可以作用于多种细胞,比如说对骨细胞导致的骨质流失、对脂肪细胞导致的体脂增加、对肝细胞导致的血清胆固醇降低。这意味着拮抗FSH不仅仅能成为AD的“解药”,或许也能够造福更多慢性病患者。
参考资料:
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