【原】抗癫痫药物的治疗范围

Therapeuticspectrum of antiseizure drugs

广谱Broad  spectrum:

被用来治疗大部分癫痫发作的药物（包括局灶性和全身性发作） Drugs used to treat a broad range of seizure types (both focal  and generalized onset)

§                                  布瓦西坦Brivaracetam  §                                  氯巴占Clobazam  §                                  非氨酯Felbamate §                                  拉莫三嗪Lamotrigine § §                                  左乙拉西坦Levetiracetam §                                  吡仑帕奈Perampanel   §                                  卢非酰胺Rufinamide §                                  托吡酯Topiramate §                                  丙戊酸Valproate §                                  唑尼沙胺Zonisamide

窄谱（局灶性）Narrow spectrum (focal):

主要用于局灶发作性的癫痫（包括局灶性发作扩展为双侧惊厥性发作）Drugs used primarily for focal-onset seizures (including focal  evolving to bilateral convulsive seizures*)

§                                  卡马西平Carbamazepine¶¶ §                                  艾司利卡西平Eslicarbazepine §                                  依佐加滨Ezogabine §                                  加巴喷丁GabapentinΔ §                                  拉科酰胺Lacosamide  §                                  奥卡西平OxcarbazepineΔ §                                  苯巴比妥Phenobarbital¶¶ §                                   苯妥英Phenytoin¶¶ §                                  普瑞巴林Pregabalin   §                                  噻加宾TiagabineΔ §                                  氨己烯酸VigabatrinΔ

窄谱（失神性）Narrow spectrum (absence):

仅用于失身型发作（一种全身性发作） Absence seizures  only (a type of generalized seizure)

§                                  乙琥胺Ethosuximide

Δ有潜在的加重特定全身性癫痫发作的可能

¶有些证据支持能控制全身强直阵挛性癫痫，但有潜在的有潜在的加重特定全身性癫痫发作的可能

§可能会加重或诱发肌阵挛性癫痫