第2章 解剖病理学中的描述性术语(Descriptive Terms in Anatomic Pathology) Central to effective learning in pathology is the ability to speak the language. This chapter covers the approach to defining and describing an unknown tumor or lesion and defines histologic terms commonly used in pathology. 学习病理学最有效方法是语言表达能力。本章涵盖了定义和描述未知肿瘤或病变的方法,并定义了病理学常用的组织学术语。 2.1与周围正常组织的界面(Interface With the Surrounding Normal Tissue)2.2细胞量(从低到高)和核分裂率(Cellularity (Low to High) and Mitotic Rate)
Note the cellularity (by cellularity we often mean how blue it is, or how densely packed the nuclei are). Cellularity may be described as hypercellular or just cellular or as hypocellular/ paucicellular. Also look for mitoses on high power. High mitotic rate may be an indicator of malignancy. Atypical mitoses (tripolar) are convincing indicators of malignancy. Estimate how many mitoses are seen per high power field (40×). 细胞量是指细胞丰富程度(我们通常所说的细胞量是指它有看上去有多蓝,或细胞核有多密集)。细胞量可描述为细胞量丰富、不加描述的细胞量或细胞量稀少/少细胞性。同时在高倍镜下寻找核分裂象。高核分裂率(或核分裂活跃)可能是恶性肿瘤的一个指标。非典型核分裂象(三极核分裂象)是恶性肿瘤令人信服的指标。估计每个高倍视野(40×)能看到多少核分裂象。 2.3结构模式(Architectural Pattern)2.4有无坏死(Presence or Absence of Necrosis)2.5细胞形状和大小,细胞质(Cell Shape and Size, Cytoplasm)Figure 2.1. Alveolar pattern, paraganglioma. Figure 2.2. Basaloid pattern and palisading, basal cell carcinoma.Figure 2.3. Cribriform pattern, adenoid cystic carcinoma.Figure 2.4. Epithelioid cells, breast carcinoma.Figure 2.5. Fascicular pattern, leiomyoma.Figure 2.6. Herringbone pattern, fibrosarcoma.Figure 2.7. Hobnailed cells, angiosarcoma.Figure 2.8. Microcystic pattern, acinic cell carcinoma.Figure 2.9. Micropapillary architecture, micropapillary serous carcinoma of the ovary carcinoma.图2.9.微乳头状结构,卵巢癌的微乳头状浆液性癌。Figure 2.10. Papillary architecture, papillary carcinoma of breast.Figure 2.11. Reticular pattern, yolk sac tumor of testis.Figure 2.12. Rosette, ependymoma. Figure 2.13. Staghorn vessels, hemangiopericytoma.Figure 2.14. Storiform pattern, dermatofibrosarcoma protuberans.Figure 2.15. Tissue culture cells, nodular fasciitis.Figure 2.16. Trabecular pattern and oncocytes, oncocytoma.Figure 2.17. Coagulative necrosis, ischemic bowel.Figure 2.18. Caseating necrosis in a granuloma, tuberculosis.Figure 2.19. Fibrinoid necrosis, pulmonary vessel. Figure 2.20. Fat necrosis, breast. Figure 2.21. Gangrenous necrosis, toe wound.Figure 2.22. Amphophilic cytoplasm, pheochromocytoma.Figure 2.23. Foamy macrophages, papillary renal cell carcinoma.Figure 2.24. Keratin, squamous cell carcinoma.Figure 2.25. Plasmacytoid, plasmacytoma.Figure 2.26. Signet-ring cells, breast carcinoma. Figure 2.27. Nuclear molding, small cell carcinoma.2.9病变的间质,如果有(Stroma of Lesion, If Present)2.10其他非细胞成分(Other Noncellular Entities)Figure 2.28. Neuroendocrine nuclei, carcinoid tumor. Figure 2.29. Cherry-red nucleolus, melanoma.Figure 2.30. Myxoid stroma, myxoid myxofibrosarcoma.Figure 2.31. Desmoplastic stroma, colon cancer.Figure 2.32. Hyaline deposits, vessels in schwannoma.Figure 2.33. Hemosiderin, nasal polyp. The Practice of Surgical Pathology:A Beginner’s Guide to the Diagnostic ProcessDiana Weedman Molavi, MD, PhDSinai Hospital, Baltimore, MarylandISBN: 978-0-387-74485-8 e-ISBN: 978-0-387-74486-5Library of Congress Control Number: 2007932936© 2008 Springer Science+Business Media, LLC仅供学习交流,不得用于其他任何途径。如有侵权,请联系删除。点击进入免疫组化小程序
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