作者:宋峻 文章来源:健康and漂亮 已授权《中国临床营养网》转载 血糖正常的人如果能够保持血糖的平稳,会得到更多的好处!
皮脂腺是雄激素的靶器官,雄性激素睾酮使皮脂腺体积增大,皮脂分泌增加,所以一般男性皮肤比女性皮肤偏油性,毛孔更粗大。男性睾丸或女性的卵巢都会合同分泌睾酮,大部分睾酮和性激素结合蛋白相结合成为结合状态的睾酮,只有1%-2%的睾酮是处于游离状态。 当食物造成血糖快速上升后,通过以下过程造成痘痘的产生: ①直接诱导皮肤角质细胞增殖和皮脂腺细胞脂质分泌,间接刺激雄激素分泌,产生炎症,参与痤疮发生; ②性激素结合球蛋白水平下降,游离睾酮增多,刺激皮脂腺大量分泌皮脂; ③高卡路里的食物通过肾上腺皮质产生更多的脱氢表雄酮和雄烯二酮,他们在外周组织转化为睾酮和双氢睾酮,引起皮脂腺分泌亢进,促进油脂分泌增加。 参考文献: 1. Li Yongze, et al., Prevalence of diabetes recorded in mainland using 2018 diagnostic criteria from the Diabetes Association: national cross pal study. BMJ 2020;369:m997 DOI: 10.1136/bmj.m997. 2. Ludwig D. Dietary glycemic index and obesity. J Nutr 2000;130(Suppl.):280Se3S. 3. Ludwig D, Majzoub J, AL-Zahrani A, Dallal G, Blanco I, Roberts S.High glycemic index foods, overeating and obesity. Pediatrics1999;103:E261e6. 4. Ball SD, Keller KR, Moyer-Mileur LJ, Ding YW, Donaldson D,Jackson WD. Prolongation of satiety after low versus moderately high glycemic index meals in obese adolescents. Pediatrics Mar 2003;111:488e94. 5. Slabber M, Barnard H, Kuyl J, Dannhauser A, Schall R. Effects of a low-insulin-response, energy-restricted diet on weight loss and plasma insulin concentrations in hyperinsulinemic obese females. Am J Clin Nutr 1994;60:48e53. 6. Bouche C, Rizkalla SW, Luo J, Vidal H, Veronese A, Pacher N, et al. Five-week, low-glycemic index diet decreases total fat mass and improves plasma lipid profile in moderately overweight nondiabetic men. Diabetes Care May 2002;25:822e8. 7.Ebbeling CB, Leidig MM, Feldman HA, Lovesky MM, Ludwig DS. Effects of a low-glycemic load vs low-fat diet in obese young adults: a randomized trial. JAMA May 16 2007;297:2092e102. 8.Larsen TM, Dalskov SM, van Baak M, Jebb SA, Papadaki A, Pfeiffer AF, et al. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med Nov 25 2010;363:2102e13. 9.Goff LM, Cowland DE, Hooper L, Frost GS. Low glycaemic index diets and blood lipids: a systematic review and meta-analysis of randomised controlled trials. Nutr Metab Cardiovasc Dis Jan 2013;23:1e10. 10. Giacco R, Parillo M, Rivellese AA, Lasorella G, Giacco A, D’Episcopo L, et al. Long-term dietary treatment with increased amounts of fiber-rich low-glycemic index natural foods improves blood glucose control and reduces the number of hypoglycemic events in type 1 diabetic patients. Diabetes Care Oct 2000;23:1461e6. 11. Parillo M, Annuzzi G, Rivellese AA, Bozzetto L, Alessandrini R,Riccardi G, et al. Effects of meals with different glycaemic index on postprandial blood glucose response in patients with type 1 diabetes treated with continuous subcutaneous insulin infusion. Diabet Med Feb 2011;28:227e9. 12. Shikany JM, Tinker LF, Neuhouser ML, Ma Y, Patterson RE, Phillips LS, et al. Association of glycemic load with cardiovascular disease risk factors: the women’s health initiative observational study. Nutrition Jun 2010;26:641e7. 13. 郭独一, 张春雷, 郑旭,等. 胰岛素抵抗的青年女性痤疮患者临床特征及诊断价值[J]. 实用皮肤病学杂志, 2022(001):015. 《中国临床营养网》编辑部 本站动态栏: |
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