在Pubmed上，用Mesh hernia repair and male infertilit检索（注意，这里用了 and 限制了关键词，即检索必须满足腹股沟疝补片修补和男性不育两个条件），共检索到30篇相关的文献。
总体上，疝的补片修补与男性的不育，还只是个“假说”，有人在动物实验上发现了用聚丙烯补片可影响输精管，但在临床观查上没有发现这方面的证据。
先看一篇最近的文献， （关于嵌顿疝病人用补片修补术后的研究，察观了术后5天、和5个月后的睾丸血流和血液中的抗精子抗体等指标）
Med Sci Monit. 2016 May 5;22:1524-33. Incarcerated Inguinal Hernia Mesh Repair: Effect on Testicular Blood Flow and Sperm Autoimmunity.Krni? D1, Dru?ijani? N1, ?tula I2, ?apkun V3, Krni? D4. AbstractBACKGROUND The aim of our study was to determine an influence of incarcerated inguinal hernia mesh repair on testicular circulation and to investigate consequent sperm autoimmunity as a possible reason for infertility. MATERIAL AND METHODS This prospective study was performed over a 3-year period, and 50 male patients were included; 25 of these patients underwent elective open meshhernia repair (Group I). Group II consisted of 25 patients who had surgery for incarcerated inguinal hernia. Doppler ultrasound evaluation of the testicular blood flow and blood samplings for antisperm antibodies (ASA) was performed in all patients before the surgery, on the second day, and 5 months after. Main outcome ultrasound measures were resistive index (RI) and pulsative index (PI), as their values are inversely proportional to testicular blood flow. RESULTS In Group I, RI, and PI temporarily increased after surgery and then returned to basal values in the late postoperative period. Friedman analysis showed a significant difference in RI and PI for all measurements in Group II (p<0.05), with="" a="" significant="" decrease="" between="" the="" preoperative,="" early,="" and="" late="" postoperative="" periods.="" all="" final="" values="" were="" within="" reference="" range,="" including="" asa,="" despite="" significant="" increase="" of="" asa="" in="" the="" late="" postoperative="" period.="" conclusions="" although="" statistically="" significant="" differences="" in="" values="" of="" testicular="" flow="" parameters="" and="" immunologic="" sensitization="" in="" observed="" time,="" final="" values="" remained="" within="" the="" reference="" ranges="" in="" all="" patients.="" our="" results="" suggest="" that="" the="">mesh probably does not cause any clinically significant effect on testicular flow and immunologic response in both groups of patients. 结论是：聚丙烯补片是安全的，未发现对男性的睾丸血流和免疫方面有任何问题。
再看一下这方面的文献综述： Am J Surg. 2012 204(4):503-9. 题目：Mechanism, assessment, and incidence of male infertility after inguinal hernia surgery: a review of the preclinical and clinical literature.（综述临床前期和临床的有关文献）Tekatli H1, Schouten N, van Dalen T, Burgmans I, Smakman N. BACKGROUND: The treatment of inguinal hernia has changed considerably over the past 15 years. We reviewed the preclinical and clinical literature to find out the effect of inguinal hernia surgery on male fertility because it has been suggested that hernia surgery may impair testicular function and male fertility. DATA SOURCES: A search on Embase, MEDLINE, and the Cochrane Library was performed to find related articles. CONCLUSIONS: Animal models show substantial effects of hernia repair on the structures in the spermatic cord, which is more pronounced in meshrepairs. Although the number of studies and the included numbers of patients were limited, clinical studies indicate that these potential adverse effects do not seem to have a clinical impact on male fertility in humans with inguinal hernias. Future clinical studies, preferably with bilateral patients, are necessary to investigate the clinical relevance of the effects of inguinal hernia and hernia surgery on male fertility. 
第三篇文章，说的是： 双侧TEP术后的男性生育的影响，（双侧可能更靠谱，因为人有两个睾丸，两条输精管）作者对58例双侧TEP术后随访超过3年，认为：只要是标准的TEP手术（补片不管是轻量还是重片，都不会对生殖功能造成影响。
World J Surg. 2011 Jul;35(7):1643-8.. Bilateral endoscopic total extraperitoneal (TEP) inguinal hernia repair does not induce obstructive azoospermia: data of a retrospective and prospective trial.Skawran S1, Weyhe D, Schmitz B, Belyaev O, Bauer KH. AbstractBACKGROUND: The endoscopic totally extraperitoneal (TEP) mesh repair is nowadays a well-established tension-free method for inguinal hernia repair. Mainly based on animal studies and case reports, a concern about the risk of postoperative infertility was expressed. This clinical study aimed to evaluate the risk of infertility due to obstructive azoospermia in men of fertile age who underwent a bilateral hernia repair. METHODS: Over 3 years (2005-2008) 59 male patients, 18-60 years of age, underwent a bilateral TEP repair. Twenty-one of them were prospectively ('light mesh') and 38 retrospectively ('heavy mesh') evaluated for testicular volume and perfusion, serum levels of sexual hormones, ejaculate volume, and number of spermatic cells. Those parameters were determined preoperatively (prospective group) and not earlier than 3 months postoperatively (both groups). RESULTS: No significant difference between pre- and postoperative values was detected in the prospectively studied group. All postoperative parameters were within the normal range in the retrospective group. There was no evidence of impaired fertility in any patient due to the operation. CONCLUSION（结论）: The standardized TEP technique for simultaneous bilateral inguinal hernia repair in male patients was not associated with a higher risk for postoperative infertility after mesh implantation. The use of heavy-weight meshes had no negative effect on fertility.（双侧男性的腹股沟疝，以标准的TEP技术，与术后男性不育无关连）
小编，今天要重点介绍以下这篇文章 刊登在《Surgery 》杂志上，2012;151:94-98)
题目Mesh hernia repair and male infertility: A retrospective register study
（疝补片修补和男性不育：一项登记的随访研究） 七步君先要解释一下有关的背景：在北欧，补片是市场是开放的，上百种的补片，什么是最好的，Ｎ多种术式，到底用什么最好，最安全有效？为此，北欧的一些国家政府建立疝病的国家数据库，即政府出钱，对疝病人进行随访登记（每登记一个病人，国家付25欧）， 所以，在此基础上建立的国家数据库，以便为国家的医疗政策方针服务。七步君再讲一下作者单位，即瑞典Karolinska医学院，Karolinska医学院是什么大学，那是发诺贝尓奖的单位，所以，信誉很高。
以下的文章就是瑞典的国家数据： 所有的入组男性患者出生年份在1950至1989年之间，同时查阅瑞典的国家不育疾病数据库系统，两数据库交叉，分析腹股沟疝补片修补术后不育的累计发病率等指标。 应该说这种数据也算大数据了，共有34,267名男性患者，这些患者至少接受过1次腹股沟疝修补手术，其中233例（0.7%）患者在接受第一次腹股沟疝无张力修补术后被确诊为不育症。与同年龄人不育症的发病没有统计学差别。（在普通的正常人中也有不育症）
结论：腹股沟疝修补使用补片，术后不会增加男性不育症风险。
Mesh hernia repair and male infertility: A retrospective register study 《Surgery 》2012;151:94-98英文摘要Abstract：BACKGROUND: Previous studies have suggested that the use of mesh in groin hernia repair may be associated with an increased risk for male infertility as a result of inflammatory obliteration of structures in the spermatic cord. In a recent study, we could not find an increased incidence of involuntary childlessness. The aim of this study was to evaluate this issue further. METHODS: Men born between 1950 and 1989, with a hernia repair registered in the Swedish Hernia Register between 1992 and 2007 were cross-linked with all men in the same age group with the diagnosis of male infertility according to the Swedish National Patient Register. The cumulative and expected incidences of infertility were analyzed. Separate multivariate logistic analyses, adjusted for age and years elapsed since the first repair, were performed for men with unilateral and bilateral repair, respectively. RESULTS: Overall, 34,267 men were identified with a history of at least 1 inguinal hernia repair. A total of 233 (0.7%) of these had been given the diagnosis of male infertility after their first operation. We did not find any differences between expected and observed cumulative incidences of infertility in men operated with hernia repair. Men with bilateral hernia repair had a slightly increased risk for infertility when mesh was used on either side. However, the cumulative incidence was less than 1%. CONCLUSION: （结论：腹股沟疝补片修补术后不会增加男性不育症风险。）Inguinal hernia repair with mesh is not associated with an increased incidence of, or clinically important risk for, male infertility.
总结 1) 从已经有的资料来看，腹股沟疝使用人工材料网片修补（聚丙烯，1958年）已经有50多年的历史，目前，每年全世界有1千多万片的临床应用（中国也超过百万），临床证据表明，用补片修补总体疗效明显好过单纯缝合修补。还没有证据证明：目前的材料与人类男性不育有关。 2) 腹股沟疝手术（无论开放和是腔镜）都要分离疝囊，操作过程可能对输精管造成威胁，补片放置是否影响术后的生育，目前还只是一个“假说”。 3) 腹股沟疝手术真正对生育功能的影响最大的因素，还是术者的操作（手术者是否规范、是否标准，是否注重细节）。目前拿补片说“事”（生育）的常见有两类人：一类是少数医生，他们可能有更高的利益追求，还常常自封自己是“疝外科的首席专家”，将自已技术绝对化，对补片说NO！；还有一类可能是卖生物补片的，这些是因为利益相关。其实你懂得！
（亮出你的观点，分享你的数据） 欢迎勾搭七步君，任何意见请在文章最后评论留言，请不吝赐教！
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